Brought to you by the Depression Is Real Coalition, The Down & Up Show is dedicated to the reality of depression. Our hosts will talk with some of the world's top experts on depression, as well as people who have been impacted by this illness. The reality of depression is that it is a debilitating and potentially deadly medical condition that affects more than 15 million Americans every year. The other reality of depression is that there is hope.

Anne Sheffield

Anne Sheffield is the author of three well-received books: "Depression Fallout: The Impact of Depression on Couples and What You Can Do To Preserve the Bond"; "Sorrow's Web: Help, Hope and Understanding for Depressed Mothers"; and "How You Can Survive When They're Depressed," winner of the Books for a Better Life Award and a Ken Award from NAMI/New York City. Daughter of a depressed mother, mother of a depressed daughter, and a longtime sufferer of depression herself, she has worked as a scientist at the Population and Development Program of the Battelle Memorial Institute and has run her own consulting firm. Anne is an advisory board member of Families for Depression Awareness, the National Foundation for Mental Health, and The Bipolar Family Treatment Center of Beth Israel Hospital, and a frequent speaker. She lives in New York City.